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Your Nerve Pain Has a Reason. Let's Find It.

If your feet burn like coals at night, your hands tingle with no warning, and every test comes back "normal" — you are not imagining it. The cause is real. It may just not have been found yet.

We look for the cause, not just the complaint.

We screen for metabolic, nutritional, and neurological drivers that are often missed when clinics treat symptoms in isolation.

Two targeted therapies, one coordinated plan.

NESA neuromodulation helps calm an overstimulated nervous system and improve sleep. Focused shockwave targets tissues that may be perpetuating pain signals.

A plan that grows with your recovery.

We space treatments based on how your system responds, and we tell you honestly when the evidence supports our approach and when it doesn't.

60-minute one-on-one assessment + treatment plan.

No pressure, no contracts.

Is This You?

If any of this sounds familiar, you're in the right place.

Burning, tingling, or electric pain in your feet and hands, often worse at night

Numbness or altered sensation in a "stocking-glove" pattern, starting in the toes and spreading upward

Living with diabetes, prediabetes, or metabolic syndrome and noticing nerve symptoms

A cancer survivor dealing with lingering nerve sensitivity or weakness after chemotherapy

Balance feels unreliable and you've changed how you walk, climb stairs, or move through your day

Medications like gabapentin or duloxetine have given you partial relief at best, and you want to understand what's actually driving the problem

The Real Problem

Why Your Nerve Pain Still Hurts After "Trying Everything"

Explore 4 slides on Ongoing nerve pain or sensitivity (burning, tingling, numbness)

Polyneuropathy is not a single disease. It is a symptom cluster with many possible drivers. When treatment targets only the pain signals and not the underlying cause, it can feel like you're filling a bathtub with the tap still running. Most people have several of these happening at once. That's why we assess the whole picture, from metabolic markers to nerve patterns to autonomic function, not just the painful region.

OUR APPROACH

The Unpain 3-Part Ongoing nerve pain or sensitivity (burning, tingling, numbness) Relief Program

INITIAL VISIT

Whole-Body Root-Cause Assessment

Detailed history review covering metabolic, nutritional, medication, and exposure factors most relevant to nerve health

Neurological screen to identify symptom pattern, distribution, and what may be driving persistence

Clear written plan with next steps, transparent pricing, and honest guidance on whether and when additional testing or referral makes sense

First 5 to 10 Weeks

Nervous System and Tissue Modulation

NESA neuromodulation: sub-sensory microcurrent therapy aimed at calming autonomic overactivity, improving sleep quality, and reducing neuropathic pain sensitivity

Focused shockwave to targeted tissues, particularly in cases where entrapment, local nerve compression, or circulatory factors are contributing to symptom persistence

Session frequency front-loaded initially, then tapered as your system stabilizes

Reduce night pain and make daily walking and activity tolerable.

10+ Weeks and Beyond

Function, Stability, and Ongoing Support

Graduated movement and balance work to rebuild confidence in walking, stepping, and managing uneven surfaces

Individualized maintenance spacing based on how your system responds, not a fixed package

Referral coordination and honest re-evaluation at each phase to ensure the plan still fits your goals

What To Expect

What Results Can I Expect?

Every case is different, but research and our clinical experience consistently show:

Many patients notice a shift in sleep quality and pain intensity within the first few weeks of NESA treatment, with continued improvement over the course of a full protocol.

In cases where focal nerve compression or entrapment is contributing, shockwave has shown measurable improvements in nerve conduction and pain reduction within 3 weeks in research studies, with gains maintained beyond 12 weeks.

Functional improvements, including more confident walking, reduced fear of stepping, and better tolerance of daily activities, are the outcomes we work toward together from the first session.

Our promise: we will tell you honestly at the assessment if we don't believe you're a good candidate for this approach. If your condition needs something different, we'll tell you and refer you directly.

EVIDENCE

The Research Behind Our Approach

Focused shockwave therapy has been shown to improve sensory nerve conduction velocity and reduce neuropathic pain in peripheral nerve disorders, based on a 2024 systematic review and meta-analysis of multiple clinical trials.

In a randomized controlled pilot study of carpal tunnel syndrome, focused shockwave produced significant reductions in pain and improvements in nerve conduction speed at 12 weeks compared to placebo.

NESA neuromodulation produced measurable changes in blood vessel diameter and autonomic markers in a 2025 randomized controlled trial in healthy adults, supporting a real physiologic effect through autonomic pathways.

Sleep quality improved meaningfully in patients receiving NESA across a 10-session pilot trial, with gains maintained at two-month follow-up, suggesting durable effects on autonomic and sleep regulation.

Evidence-based guidelines for distal symmetric polyneuropathy recommend targeted evaluation for glucose dysregulation, vitamin B12 deficiency, and paraprotein markers as the foundation of any diagnostic and treatment plan.

Outcomes are group averages from clinical trials; individual results vary.

See full references
  1. [1] Callaghan BC, Price RS, Feldman EL. Distal Symmetric Polyneuropathy: A Review. JAMA. 2015. DOI: 10.1001/jama.2015.13611. pubmed.ncbi.nlm.nih.gov/26599185
  2. [2] Callaghan BC, Price RS, Feldman EL. Distal Symmetric Polyneuropathy in 2020. JAMA. 2020. DOI: 10.1001/jama.2020.0700. pubmed.ncbi.nlm.nih.gov/32633792
  3. [3] England JD, Gronseth GS, Franklin G, et al. Evaluation of distal symmetric polyneuropathy: the role of laboratory and genetic testing. Muscle Nerve. 2009. DOI: 10.1002/mus.21226. pubmed.ncbi.nlm.nih.gov/19086068
  4. [4] Zhou P, et al. Prevalence and risk factors for painful diabetic peripheral neuropathy: a systematic review and meta-analysis. Front Neurol. 2025. DOI: 10.3389/fneur.2025.1564867. pubmed.ncbi.nlm.nih.gov/40433609
  5. [5] D'Souza RS, et al. Neuromodulation Therapy for Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review. Biomedicines. 2022. DOI: 10.3390/biomedicines10081909. pubmed.ncbi.nlm.nih.gov/36009456
  6. [6] Yang L, et al. Effect of extracorporeal shock wave therapy on nerve conduction: a systematic review and meta-analysis. Front Neurol. 2024. DOI: 10.3389/fneur.2024.1493692. pubmed.ncbi.nlm.nih.gov/39650239
  7. [7] Gesslbauer C, et al. Effectiveness of focused extracorporeal shock wave therapy in the treatment of carpal tunnel syndrome: A randomized, placebo-controlled pilot study. Wien Klin Wochenschr. 2021. DOI: 10.1007/s00508-020-01785-9. pubmed.ncbi.nlm.nih.gov/33351153
  8. [8] Mínguez-Esteban I, et al. Acute sonographic changes in common carotid artery after NESA neuromodulation intervention in healthy adults: a randomized controlled clinical trial. Front Neurosci. 2025. DOI: 10.3389/fnins.2025.1526236. pubmed.ncbi.nlm.nih.gov/40356697
  9. [9] Blasco-Bonora PM, et al. Non-Invasive Autonomic Neuromodulation for Overactive Bladder: A Comparative Pilot Trial of NESA and Tibial Nerve Stimulation. J Clin Med. 2025. DOI: 10.3390/jcm14248881. pubmed.ncbi.nlm.nih.gov/41464783
  10. [10] Azevedo N, Medina-Ramírez R. Pain and the autonomic nervous system. The role of non-invasive neuromodulation with NESA microcurrents. Front Pain Res (Lausanne). 2025. DOI: 10.3389/fpain.2025.1410808. pubmed.ncbi.nlm.nih.gov/40034400
  11. [11] Hoitsma E, et al. Sarcoidosis and Pain Caused by Small-Fiber Neuropathy. Pain Res Treat. 2012. pmc.ncbi.nlm.nih.gov/articles/PMC3523152

Ongoing nerve pain or sensitivity (burning, tingling, numbness)FAQ

Here are answers to some of the most common questions about Ongoing nerve pain or sensitivity (burning, tingling, numbness).

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What are the best non-drug treatments for neuropathy pain?

The most supported non-drug approaches are those that either address the underlying cause or directly target the nervous system's processing of pain signals. At Unpain, we use NESA neuromodulation to work with the autonomic nervous system and sleep regulation, and focused shockwave to address tissues or focal compressions that may be contributing. Neither is a substitute for treating the root cause, which is why we assess that first. We map this out in your first visit.

Can shockwave therapy help nerve pain or numbness?

The strongest evidence for shockwave in nerve-related conditions comes from focal entrapment neuropathies like carpal tunnel syndrome, where randomized trials have shown improvements in both pain and nerve conduction. For diffuse polyneuropathy, evidence is emerging rather than established. Where shockwave fits best is when there is a focal tissue or compression component contributing to a patient's nerve symptoms. We assess this specifically during your initial visit.

Why is my neuropathy worse at night?

Night-time worsening is a well-recognized feature of small-fibre neuropathy. During the day, movement, distraction, and other sensory input compete with pain signals. At night, that background noise drops away, and burning, tingling, and skin sensitivity can become overwhelming. Autonomic activity also shifts during sleep, which can amplify nerve discomfort in susceptible people. Addressing autonomic regulation and sleep quality is one of the reasons we include NESA in the treatment approach for these presentations. We review this with you during your initial assessment.

Why does my neuropathy keep coming back after it seemed better?

Neuropathy symptoms tend to recur or fluctuate when the underlying driver has not been fully corrected. If blood sugar remains elevated, B12 stays low, or another trigger is still active, the nerve damage process continues even when pain temporarily improves. A flare-up often signals that the system is still under load, not that treatment has failed. This is exactly why our first visit focuses on identifying what is driving the problem, not just what is hurting.

How many sessions do people typically need for nerve pain?

Published NESA trials have studied protocols of around 10 sessions over 5 weeks for autonomic and sleep-related outcomes. Shockwave studies for peripheral nerve conditions have used 3 weekly sessions as a starting protocol. In practice, neuropathy presentations vary widely by cause, severity, and chronicity, so we individualize based on how your system responds. We are transparent about session counts and costs from the first visit, and there is no obligation to commit to a full package upfront.

What do I do if gabapentin or other medications didn't help my neuropathy?

Medications for neuropathic pain are designed to reduce the signal, not fix the source. If they gave limited relief, it often means the underlying driver is still active or the nervous system's sensitization is deeper than symptom management can reach on its own. We don't replace your medical team, but we can work alongside them to address things that medications typically don't touch: root-cause identification, autonomic regulation, sleep quality, and targeted tissue work. We review this with you during your initial assessment.

YOUR NEXT STEP

Ready to See What's Actually Driving Your Nerve Pain?

Stop managing a symptom. Get a plan that identifies the driver, calms the system, and targets the right structures, not just the painful ones.

Initial Ongoing nerve pain or sensitivity (burning, tingling, numbness) Assessment — Edmonton

60-minute one-on-one session. Here’s what’s included:

1

Full neurological and movement screen covering the spine, lower limbs, and autonomic indicators

2

Identify which pain drivers are most relevant for your specific presentation

3

Review of your history, imaging, and any previous test results you bring

4

Clear written plan with transparent pricing before you commit to anything further

No referral needed. No obligation to continue beyond the first visit.

No pressure, no contracts.

We will tell you honestly at the assessment if we don't believe you're a good candidate for this approach. If your condition needs something different, we'll refer you directly.