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The Scar Tissue Can Break Down. Your Intimacy Can Come Back.

If you've noticed a curve, felt pain during erections, or found yourself avoiding intimacy out of fear — you're not alone, and you're not out of options.

We assess the actual tissue, not just the symptom.

We evaluate plaque characteristics, deformity stage, and your healing biology to understand what's really driving the condition.

Focused shockwave is the difference.

Not all shockwave devices are equal. We use true focal shockwave therapy — the technology validated in clinical trials for Peyronie's disease — not radial pressure wave devices.

We tell you the truth.

If your case is better suited to a surgical referral, we'll say so at the assessment — before you spend any money on treatment.

60-minute one-on-one assessment + treatment plan.

No pressure, no contracts.

Is This You?

If any of this sounds familiar, you're in the right place.

Pain or aching during erections, or even when you're not aroused

A visible curve or bend that wasn't there before

A palpable lump or hardness you can feel in the shaft

Shortening, narrowing, or an "hourglass" shape when erect

A history of Dupuytren's contracture in your hands or fingers

You've tried supplements, topical creams, or stretching devices with little to no improvement

You're avoiding intimacy out of fear of making things worse — and want a real, non-surgical plan before you commit to anything else

The Real Problem

Why the Curve and Pain Persist After "Trying Everything"

Explore 4 slides on Peyronie's Disease

Peyronie's disease is a scar tissue condition, not a circulation problem or a hormone imbalance. Unless treatment directly addresses the fibrotic plaque — the hardened, abnormal tissue inside the shaft — the underlying cause remains untouched. Most patients have several of these happening at once. That's why we assess the full picture — the tissue stage, the degree of deformity, and your individual healing biology — not just the curvature angle.

OUR APPROACH

The Unpain 3-Part Peyronie's Disease Relief Program

INITIAL VISIT

Whole-Body Root-Cause Assessment

Full assessment of plaque characteristics — size, location, deformity degree, and stage (active vs. stable)

Review of your health history, including any connective tissue conditions such as Dupuytren's contracture

Clear written treatment plan with transparent pricing before you commit to anything

First 6 to 10 Weeks

Targeted Scar Tissue Modulation

Focused shockwave therapy delivered directly to the plaque — acoustic energy that influences tissue remodelling biology and has been shown to reduce pain and plaque size in clinical trials

EMTT (electromagnetic transduction therapy) to support tissue-level healing and reduce inflammation around the plaque, used as an adjunct to shockwave

Guidance on movement and activity modification to reduce re-injury risk during the active phase

Reduce pain, begin breaking down scar tissue, and slow active-phase progression.

10+ Weeks and Beyond

Stabilization and Protective Aftercare

Monitoring of plaque characteristics and deformity as the condition transitions toward the stable phase

Continued activity guidance and protective strategies to reduce the risk of re-injury and progression

Long-term check-ins to catch early signs of change and adjust the approach accordingly

What To Expect

What Results Can I Expect?

Every case is different, but research and our clinical experience consistently show:

Pain during erections is often the first symptom to improve. Clinical trial data show a statistically significant reduction in erection-related pain with focused shockwave therapy compared to patients who received no active treatment.

A meaningful subset of patients experience a measurable reduction in plaque size, which can reduce the degree of deformity. Pooled trial data show more than twice the rate of plaque size reduction compared to no treatment. Curvature outcomes are more variable and are discussed honestly at your assessment.

For men with mild-to-moderate deformity, focused non-surgical treatment may delay or reduce the need for surgical intervention. Cases with severe or significantly progressed deformity are better served by surgical referral — and we will tell you that directly if it applies to you.

Our promise: we will tell you honestly at the assessment if we don't believe you're a good candidate for this approach — before any treatment begins.

EVIDENCE

The Research Behind Our Approach

Focused shockwave therapy has been shown to significantly reduce pain during erections in sham-controlled randomized trials, with a statistically meaningful difference compared to patients who received no active treatment.

In pooled trial data, more than twice as many patients experienced a measurable reduction in plaque size with focused shockwave therapy compared to those who received no active treatment.

The American Urological Association conditionally recommends focused shockwave therapy for Peyronie's-related penile pain, while advising that curvature and plaque-reduction claims be communicated accurately to patients.

EMTT combined with shockwave therapy has demonstrated meaningfully greater pain reduction and functional improvement compared to shockwave alone in randomized controlled trials for soft-tissue conditions, supporting its use as an adjunctive therapy.

Research consistently identifies repetitive penile microtrauma combined with a genetic predisposition to abnormal scar formation — including links to Dupuytren's contracture — as the primary driver of fibrotic plaque development in Peyronie's disease.

Outcomes are group averages from clinical trials; individual results vary.

See full references
  1. [1] Nehra A, Alterowitz R, Culkin DJ, et al. Peyronie's Disease: AUA Guideline. J Urol. 2015. pmc.ncbi.nlm.nih.gov/articles/PMC5027990
  2. [2] Wang X, et al. Updated recommendations on the therapeutic role of extracorporeal shock wave therapy for Peyronie's disease: systematic review and meta-analysis (RCT-only). Transl Androl Urol. 2023. pmc.ncbi.nlm.nih.gov/articles/PMC10498627
  3. [3] Al-Thakafi S, Al-Hathal N. Peyronie's disease: a literature review on epidemiology, genetics, pathophysiology, diagnosis and work-up. Transl Androl Urol. 2016. pmc.ncbi.nlm.nih.gov/articles/PMC4893516
  4. [4] Di Maida F, Maruccia S, Minervini A, et al. The Natural History of Peyronie's Disease. World J Mens Health. 2020. pmc.ncbi.nlm.nih.gov/articles/PMC8255406
  5. [5] Douroumis K, et al. Acute Phase Peyronie's Disease: Where Do We Stand? 2024. pmc.ncbi.nlm.nih.gov/articles/PMC11403542
  6. [6] Mulhall JP, Schiff J, Guhring P. An analysis of the natural history of Peyronie's disease. J Urol. 2006. pubmed.ncbi.nlm.nih.gov/16697815
  7. [7] Nugteren HM, Nijman JM, et al. The association between Peyronie's and Dupuytren's disease. J Sex Med. 2011. pubmed.ncbi.nlm.nih.gov/21633367
  8. [8] Klüter T, Krath A, Stukenberg M, et al. Electromagnetic transduction therapy and shockwave therapy in 86 patients with rotator cuff tendinopathy: a prospective randomized controlled trial. Electromagn Biol Med. 2018. pubmed.ncbi.nlm.nih.gov/30183430
  9. [9] Krath A, Klüter T, Stukenberg M, et al. Electromagnetic transduction therapy in non-specific low back pain: a prospective randomized controlled trial. J Orthop. 2017. pmc.ncbi.nlm.nih.gov/articles/PMC5510490
  10. [10] Mancini M, et al. Electromagnetic Transduction Therapy (EMTT) Enhances Tenocyte Regenerative Potential: Evidence for Senolytic-like Effects and Matrix Remodeling. Int J Mol Sci. 2025. pmc.ncbi.nlm.nih.gov/articles/PMC12346084

BY THE NUMBERS

What the Research Shows

These figures come from sham-controlled randomized trials and meta-analyses on focused shockwave therapy for Peyronie's disease.

Data from sham-controlled RCTs and peer-reviewed meta-analyses. Individual outcomes vary. Group averages from clinical trials do not guarantee individual results.

Peyronie's DiseaseFAQ

Here are answers to some of the most common questions about Peyronie's Disease.

6 results found

Does focused shockwave therapy actually work for Peyronie's disease?

The most consistent benefit seen in sham-controlled trials is pain reduction. Some patients also experience a reduction in plaque size. Curvature outcomes are more variable — pooled trial data show improvement in some patients, but the effect is not statistically significant when compared to sham treatment. The American Urological Association conditionally recommends focused shockwave for Peyronie's-related pain and advises transparent communication about what it can and cannot reliably change. We discuss all of this honestly at your assessment.

What actually causes the scar tissue to form in the first place?

Small injuries to the tissue surrounding the shaft happen during intercourse and erection. In most men, these micro-tears heal without issue. In men with a genetic predisposition to abnormal scarring — including those with a history of Dupuytren's contracture — the body's repair process produces scar tissue instead of normal tissue. That accumulated scar tissue forms the plaque responsible for the curve, pain, and deformity. We map this out in your first visit.

What's the difference between focused shockwave and radial shockwave for Peyronie's?

Focused (or "true focal") shockwave delivers acoustic energy to a precise target deep in tissue — which is what the clinical trial base for Peyronie's disease uses. Radial pressure wave devices scatter energy more broadly and are primarily used for superficial musculoskeletal conditions. At Unpain, we use true focal shockwave technology for Peyronie's. In our clinical experience, the correct device matters for this condition. We review this with you during your initial assessment.

How many sessions are typically needed?

Our clinical protocol typically runs 10 to 12 sessions, which is higher than the 4 to 6 sessions used in many published trials. The difference reflects our combination approach — focused shockwave plus EMTT — and real-world severity variation. The exact number for your case depends on the degree of deformity, plaque characteristics, and how you respond to early treatment. We outline a realistic estimate at your first visit.

Does Peyronie's disease get worse over time if left untreated?

During the active phase, curvature can increase in a meaningful proportion of men — progression occurs in some patients while others remain stable, and a smaller subset see spontaneous improvement. Pain, on the other hand, often improves over time even without intervention. This is important context: the goal of early non-surgical treatment is to interrupt progression during the active phase, when tissue is still remodelling. Waiting until the plaque fully matures can reduce responsiveness. We review your timeline and stage at your assessment.

When should I consider surgery instead of non-surgical treatment?

Surgery is typically reserved for men with stable disease — meaning the deformity has not changed for at least three months — and whose curvature or deformity is severe enough to prevent sexual activity. If we assess you and find that the degree of deformity places you in a category better served by surgical evaluation, we will tell you directly and refer you appropriately. Non-surgical approaches tend to respond best in cases of lower-degree deformity. We will always give you an honest picture at the assessment.

YOUR NEXT STEP

Ready to See What's Actually Driving the Deformity?

Stop guessing and collecting random treatments. Get a plan that targets the scar tissue directly, not just the symptoms.

Initial Peyronie's Disease Assessment — Edmonton

60-minute one-on-one session. Here’s what’s included:

1

Plaque assessment — characteristics, location, degree of deformity, and current disease phase

2

Identification of your individual risk and healing biology factors

3

Review of history and any available imaging or prior treatment records

4

Clear written plan with transparent pricing before you commit to anything

No referral needed. No obligation to continue beyond the first visit.

No pressure, no contracts.

We will tell you honestly at the assessment if we don't believe you're a good candidate for this approach. If your condition needs something different, we'll refer you directly.