You've tried resting. You've tried pacing. Maybe you've even tried pushing through. But the crashes keep coming, the brain fog won't lift, and your energy feels like it hits a wall you can't predict. What's happening in your body is real, and it's more than fatigue.
We assess the whole system, not just your fatigue level.
We map your autonomic patterns, pain sensitization, sleep disruption, and exertional tolerance together, because long COVID affects all of them at once.
NESA neuromodulation targets the nervous system drivers directly.
Sub-sensory, non-invasive, and studied specifically in post-COVID condition, NESA works alongside your care plan, not as a stand-alone fix.
We build capacity around your crash threshold, not past it.
Symptom-titrated progression means we never push you into a flare. Every step forward is paced and earned, with ongoing support as your envelope expands.
60-minute one-on-one assessment + treatment plan.
No pressure, no contracts.
If any of this sounds familiar, you're in the right place.
A shower, a short walk, or a single busy day wipes you out for hours or days after
Your brain feels slow, foggy, or disconnected, even on a "good" day
You sleep 8, 10, even 12 hours and still wake up exhausted and unrefreshed
Your heart races, you feel lightheaded, or shaky when you stand up
Work feels impossible at full capacity, and modified duties barely feel sustainable
You've tried rest, supplements, generic rehab, and pacing, and you're still stuck in the crash-recover-crash cycle
You want someone to actually look at why this keeps happening, not just hand you more exercises or tell you to be patient
The Real Problem
Explore 4 slides on Post-viral fatigue, including long COVID symptoms
Long COVID isn't a single problem. Research confirms it's a multi-system condition where several biological drivers interact at once. Most treatments fail because they target one thread. Here are the four patterns we most commonly see driving persistent symptoms. Most people have several of these patterns active at the same time. That's why we assess the whole system, from nervous system regulation to exertional capacity, not just the symptom that showed up loudest today.
OUR APPROACH
INITIAL VISIT
Map your autonomic patterns, exertional tolerance, sleep quality, and pain sensitization together
Identify which drivers are most dominant in your case: nervous system, immune load, circulatory, or mixed
Leave with a clear written plan and transparent pricing before you commit to anything further
Weeks 1 to 8
NESA sub-sensory neuromodulation to support autonomic regulation, delivered in a course of approximately 15 sessions over 2 months
Structured pacing protocols individualized to your crash threshold, so we reduce flare frequency without triggering setbacks
Ongoing monitoring of fatigue, sleep, and activity tolerance to track signals and adjust the plan in real time
Reduce crash frequency and stabilize your sleep and energy baseline.
8+ Weeks and Beyond
Individually designed, symptom-titrated activity progression, building your energy envelope gradually and safely
Physiotherapy-guided movement and strength reintroduction calibrated to your functional baseline, not a generic protocol
Ongoing coaching and check-ins to catch early warning signs of relapse and adjust before a crash occurs
What To Expect
Every case is different, but research and our clinical experience consistently show:
Early signals within 4 to 6 weeks. In the studied NESA post-COVID protocol, measurable changes in fatigue impact and autonomic markers were observed at the mid-point of a 15-session course. These are signals, not finish lines.
Functional gains that matter in daily life. Patients in structured pacing and symptom-titrated rehabilitation programs have shown improvements in fatigue severity, sleep quality, and physical performance capacity. For most people, the goal is to expand what a normal day can include without triggering a crash.
A plan, not more waiting. Return-to-work and return-to-activity in long COVID often requires graded, professionally guided re-entry, not aggressive pushing. We give you a structured path forward with clearly defined milestones.
Our promise: we will tell you honestly at the assessment if we don't believe you're a good candidate for this approach.
EVIDENCE
NESA neuromodulation has been studied in a triple-blind, placebo-controlled pilot in women with post-COVID-19 condition, tracking fatigue impact, sleep quality, heart rate variability, and pain sensitivity across a 15-session, 2-month protocol.
Autonomic nervous system markers, specifically heart rate variability metrics including SDNN, showed measurable differences between active and placebo groups in the post-COVID NESA pilot, supporting the nervous-system rationale for this approach in dysautonomia-type presentations.
A 2025 randomized controlled trial in healthy adults found that a single 20-minute NESA session produced immediate measurable changes in carotid artery parameters, suggesting the therapy can acutely influence vascular-autonomic regulation.
A 2024 randomized controlled trial found that a symptom-titrated, individualized exercise program significantly improved fatigue severity and health-related quality of life in people with post-COVID condition, compared to a control group.
A 2024 prospective cohort study (PACELOC) showed that a structured pacing and active rest program reduced post-exertional symptom exacerbation frequency week over week across an 8-week program, with follow-up data at 12 weeks supporting short-term durability.
Outcomes are group averages from clinical trials; individual results vary. NESA evidence in post-COVID populations is best characterized as early-stage, based on a small pilot trial. Larger studies are ongoing.
Here are answers to some of the most common questions about Post-viral fatigue, including long COVID symptoms.
6 results found
NESA delivers sub-sensory microcurrents, meaning you don't feel them. The goal is to target the autonomic nervous system rather than create a local muscle or nerve stimulation effect. TENS works at a sensory or motor threshold and is typically used for pain relief in a specific area. NESA is designed as a whole-system regulation approach, which is why it's used for conditions like post-viral fatigue where the nervous system itself is a primary driver. We walk through what to expect during your initial assessment.
Most likely several things at once. Current research points to interacting mechanisms, including autonomic dysregulation, persistent immune activation, microvascular dysfunction, and in some cases, reactivation of latent viruses like EBV. This heterogeneity is exactly why a single-cause treatment rarely works. Our assessment identifies which pattern appears dominant in your case before building a plan.
The post-COVID research protocol used 15 sessions delivered over approximately 2 months, roughly 3 sessions per week on alternating days. In a clinical setting, the number of sessions is adapted to your individual response, scheduling, and how your symptoms behave. We use the research protocol as a planning anchor but always adjust based on how you're actually responding. We review this with you during your initial assessment.
Post-exertional symptom exacerbation in long COVID can be triggered by amounts of activity that feel minor, and the symptom delay (sometimes 24 to 48 hours) makes it hard to connect cause and effect. Without knowing your specific threshold and without addressing the underlying nervous system and physiologic drivers, pacing alone often isn't enough. Research supports structured, professionally guided pacing with real-time monitoring, not just "do less." We map your crash pattern in detail during your first visit.
Generic exercise prescription can be harmful in PESE-dominant long COVID, and research is clear that pushing through is not an appropriate strategy for this population. Symptom-titrated exercise, where intensity and volume are carefully calibrated to stay below your exacerbation threshold, has shown improvements in fatigue and quality of life in appropriate patient cohorts. The key word is individualized. We do not apply a standard protocol until we know your threshold. We review this with you during your initial assessment.
Unpain Clinic offers assessment and treatment for post-viral fatigue and long COVID using a multi-driver approach that includes NESA neuromodulation, symptom-titrated physiotherapy, and structured load management. Our initial assessment is 60 minutes, one-on-one, and designed to identify what's actually driving your symptoms before any treatment begins. No referral is needed and there is no obligation to continue beyond the first visit.
YOUR NEXT STEP
Stop guessing, stop collecting random treatments, and get a plan that addresses the system, not just the symptom that happened to show up loudest today.
Initial Post-viral fatigue, including long COVID symptoms Assessment — Edmonton
60-minute one-on-one session. Here’s what’s included:
Full assessment of autonomic patterns, exertional tolerance, sleep quality, and pain sensitization
Identify which drivers are most active in your case and which interventions are most appropriate
Review of your history, previous treatments, and any available investigations
Clear written plan with transparent pricing before you commit to anything beyond the first visit
No referral needed. No obligation to continue beyond the first visit.
No pressure, no contracts.
We will tell you honestly at the assessment if we don't believe you're a good candidate for this approach. If your condition needs something different, we'll refer you directly.
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