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When Tests Come Back Normal But The Pain Never Stops

You've been told everything looks fine. But the burning, stinging, and pain with touch are very real, and they're affecting your intimacy, your daily life, and your sense of self. You deserve answers, not another prescription that doesn't work.

We assess the whole system — not just the painful area.

Vulvodynia is driven by nerve sensitivity, pelvic floor tension, hormonal factors, and more. We identify which ones apply to you.

Advanced therapies target the drivers, not just the symptoms.

We combine pelvic floor physiotherapy, shockwave therapy, and neuromodulation in a sequenced approach backed by clinical research.

Long-term support, not a short-term patch.

We track your progress and adjust your plan over time. Benefits from physiotherapy often continue building months after sessions end.

60-minute one-on-one assessment + treatment plan.

No pressure, no contracts.

Is This You?

If any of this sounds familiar, you're in the right place.

Burning, stinging, or rawness that has lasted for months — even though every test came back negative

Pain with penetration, tampon use, tight clothing, or even sitting for long periods

You've tried antifungal creams, lidocaine, or antibiotics and nothing has made a lasting difference

Your pelvic floor feels "too tight" or guarded — not weak — but no one has addressed that

Your symptoms started after a hormonal change, a round of yeast infections, or a period of high stress

You've been dismissed or told it's "in your head," and you want a clinician who actually investigates what's driving the pain

The Real Problem

Why Your Vulvar Pain Keeps Coming Back After "Trying Everything"

Explore 4 slides on Vulvodynia Pain

Vulvodynia is not one thing. It's a condition with multiple overlapping drivers — and most treatment approaches only address one of them. When the underlying causes are missed, symptoms cycle back. Here's what the research actually shows is happening. Most people have several of these happening at once. That's why we assess the whole picture — from the nervous system and pelvic floor to hormonal history and prior infections — not just the painful spot.

OUR APPROACH

The Unpain 3-Part Vulvodynia Pain Relief Program

INITIAL VISIT

Whole-Body Root-Cause Assessment

Detailed intake of symptom history, hormonal changes, prior treatments, and pain triggers

Pelvic floor muscle tone assessment to identify guarding, hypertonicity, and myofascial trigger points

Nervous system and pain sensitization screening to understand how central or peripheral your drivers are

You leave with a written plan and clear pricing before committing to anything further

Weeks 1 to 8

Pain and Nerve Modulation

Focused shockwave therapy applied perineally — typically 6 to 8 sessions — to reduce nerve irritation and local tissue sensitivity

NESA microcurrent neuromodulation — typically 10 to 20 sessions — to calm central and autonomic nervous system overactivation

Pelvic floor physiotherapy with biofeedback, manual therapy, and progressive desensitization — aligned with a 10-session RCT protocol for provoked vestibulodynia

Reduce provoked pain, improve tolerance to touch, and calm the overactive alarm system.

Week 8 and Beyond

Progressive Rehabilitation and Long-Term Aftercare

Pelvic floor coordination and relaxation training to maintain gains and prevent guarding from returning

Education on lifestyle factors and triggers — including dietary considerations, bowel and bladder habits, and stress contributors

Ongoing monitoring with clear milestones, and an open door to return if symptoms fluctuate

What To Expect

What Results Can I Expect?

Every case is different, but research and our clinical experience consistently show:

Early signs of improvement with shockwave therapy can appear within the first week of treatment in clinical trials. Meaningful reductions in pain scores and provoked sensitivity have been measured at 12 weeks post-treatment.

Multimodal pelvic floor physiotherapy produces sustained reductions in pain with penetration — with benefits maintained at 6-month follow-up in clinical research. Many patients report their greatest improvement in the months after treatment ends, as the nervous system continues to settle.

When the right combination of drivers is addressed, many patients see meaningful improvements in sexual function, daily comfort, and quality of life — the areas that matter most and are hardest to recover without targeted care.

Our promise: we will tell you at the assessment if we don't believe you're a good candidate for this approach. If your situation needs a different kind of care, we will refer you directly.

EVIDENCE

The Research Behind Our Approach

Multimodal pelvic floor physiotherapy has been shown to outperform topical lidocaine for provoked vestibulodynia, with significant between-group differences sustained at 6 months, confirmed in a multicentre randomized trial.

Focused extracorporeal shockwave therapy has been shown to substantially reduce vulvodynia pain scores and provoked sensitivity on clinical testing, compared to placebo, in a prospective double-blind randomized trial.

Low-intensity shockwave therapy for provoked vestibulodynia has been shown to improve both pain scores and validated sexual function measures by 3 months post-treatment in a double-blind sham-controlled randomized trial.

A modulated TENS neuromodulation protocol has been shown to produce clinically meaningful reductions in burning pain and dyspareunia over 120 days in a randomized controlled trial for vestibulodynia.

Long-term follow-up data from physiotherapy-treated patients (mean 13 years post-treatment) found that 42% reported no intercourse pain since completing therapy, with maximal improvement often occurring months after sessions ended.

Outcomes are group averages from clinical trials; individual results vary.

See full references
  1. [1] Bornstein J et al. 2015 ISSVD, ISSWSH and IPPS Consensus Terminology and Classification of Persistent Vulvar Pain and Vulvodynia. Obstetrics & Gynecology. 2016. doi:10.1097/AOG.0000000000001279
  2. [2] Pukall CF et al. Vulvodynia: Definition, Prevalence, Impact, and Pathophysiological Factors. Journal of Sexual Medicine. 2016;13:291–304
  3. [3] Morin M et al. Multimodal physical therapy versus topical lidocaine for provoked vestibulodynia: a multicenter, randomized trial. American Journal of Obstetrics and Gynecology. 2021;224(2):189.e1–189.e12. doi:10.1016/j.ajog.2020.08.038
  4. [4] Jahshan-Doukhy O et al. Long-Term Efficacy of Physical Therapy for Localized Provoked Vulvodynia. International Journal of Women's Health. 2021
  5. [5] Hurt K et al. Extracorporeal Shock Wave Therapy for Treatment of Vulvodynia: A prospective, randomized, double-blind, placebo-controlled study. European Journal of Physical and Rehabilitation Medicine. 2020. doi:10.23736/S1973-9087.20.05903-1
  6. [6] Gruenwald I et al. Low-Intensity Shockwave for Treatment of Vestibulodynia: A Randomized Controlled Therapy Trial. Journal of Sexual Medicine. 2021;18:347–352
  7. [7] Murina F et al. Effectiveness of Two TENS Protocols in Women with Provoked Vestibulodynia: A Randomized Controlled Trial. 2023
  8. [8] Harlow BL et al. A population-based assessment of chronic unexplained vulvar pain: have we underestimated the prevalence of vulvodynia? J Am Med Womens Assoc. 2003
  9. [9] Reed BD et al. Factors Associated With Vulvodynia Incidence. Obstetrics & Gynecology. 2014
  10. [10] Nguyen RHN et al. Remission of Vulvar Pain among Women with Primary Vulvodynia. J Low Genit Tract Dis. 2015
  11. [11] Reed BD et al. Recurrent Yeast Infections and Vulvodynia. PubMed Central
  12. [12] Jeremias J et al. Interleukin 1 receptor antagonist gene polymorphism in women with vulvar vestibulitis. Am J Obstet Gynecol. 2000. doi:10.1016/S0002-9378(00)70212-2
  13. [13] Awad-Igbaria A et al. Inflammation-induced mast cell-derived nerve growth factor: a key player in chronic vulvar pain? 2025
  14. [14] Reed BD et al. Oral contraceptive use and risk of vulvodynia: a population-based longitudinal study. 2013
  15. [15] Ghizzani A et al. Differentiating overlapping symptoms of vulvodynia and pudendal neuralgia. PubMed Central. 2018
  16. [16] d'Agostino MC et al. Shock wave as biological therapeutic tool: From mechanical stimulation to recovery and healing, through mechanotransduction. International Journal of Surgery. 2015
  17. [17] Rubal M et al. Managing Vulvodynia with Central Sensitization: Challenges and Strategies. PubMed Central. 2023
  18. [18] Azevedo N, Medina-Ramírez R. Pain and the autonomic nervous system. The role of non-invasive neuromodulation with NESA microcurrents. Frontiers in Pain Research. 2025. doi:10.3389/fpain.2025.1410808
  19. [19] Mínguez-Esteban I et al. Acute sonographic changes in common carotid artery after NESA neuromodulation intervention in healthy adults: a randomized controlled clinical trial. PubMed Central. 2025
  20. [20] NESA® Neuromodulation at Unpain Clinic. unpainclinic.com/nesa-neuromodulation-unpain-clinic-edmonton
  21. [21] Pelvic pain treatment page. Unpain Clinic. unpainclinic.com/all-treatments/pelvic-pain-treatment-in-edmonton
  22. [22] Why pelvic pain persists. Unpain Clinic. unpainclinic.com/pelvic-pain-symptoms-edmonton

BY THE NUMBERS

What the Research Shows

These figures come from peer-reviewed randomized controlled trials. Individual results vary.

Vulvodynia PainFAQ

Here are answers to some of the most common questions about Vulvodynia Pain.

6 results found

Does pelvic floor physiotherapy actually help provoked vestibulodynia?

Yes — and there is good quality clinical evidence to support it. A large multicentre randomized trial found that multimodal pelvic floor physiotherapy produced significantly greater pain reduction than overnight topical lidocaine, with 79% of patients reporting meaningful improvement compared to 39% in the lidocaine group. The benefits were maintained at six months. We review your individual presentation and treatment history at your first visit to see how this fits your case.

Can pelvic floor muscle tightness actually cause vulvar burning or stabbing pain?

Yes. Pelvic floor hypertonicity — meaning the muscles are chronically braced, not weak — creates ongoing mechanical and neural pressure at the vestibule. This can produce burning, stabbing, and aching that feels indistinguishable from nerve pain. In many patients, this muscle tension is the missing piece that previous treatments never assessed. We check pelvic floor tone as part of your initial assessment.

Is shockwave therapy used for vulvodynia, and how does it work?

Yes. Focused shockwave therapy has been studied for vulvodynia and provoked vestibulodynia in randomized placebo-controlled trials. It is applied perineally and works by producing analgesic effects on local nerves while supporting tissue-level changes associated with inflammation modulation. Clinical trials have used 4 to 12 sessions. Our founder typically uses 6 to 8 sessions as part of a combined approach. We map out the full protocol at your assessment.

How many physiotherapy sessions are typically needed for provoked vestibulodynia?

The key clinical trial used 10 weekly physiotherapy sessions. Many patients report that their improvement continued to build in the 3 to 6 months after those sessions ended — meaning the treatment works progressively, not all at once. Your plan will depend on your specific drivers and how your body responds. We outline realistic timelines at your first visit.

Why does vulvodynia keep coming back even when it seems to improve?

Vulvodynia can have an episodic course — it is not always a one-way journey to resolution. Recurrence often happens when underlying drivers are not fully addressed: central sensitization that was never targeted, pelvic floor tension that returns with stress, or hormonal and lifestyle triggers that weren't identified. Some phenotypes are also more prone to fluctuation than others. Understanding your specific drivers is the first step to breaking the cycle. We discuss this directly at your assessment.

What do I do if creams, antifungals, and lidocaine haven't helped?

This is one of the most common situations we see. Topical treatments target the surface, but vulvodynia is often driven by processes deeper in the nervous system and pelvic floor. If those drivers are not addressed, surface treatments provide limited or temporary relief at best. A structured assessment that maps your specific drivers — nerve sensitivity, muscle tension, central amplification — can clarify what has and hasn't been addressed, and open a different path forward.

YOUR NEXT STEP

Ready to See What's Actually Driving Your Vulvar Pain?

Stop cycling through treatments that address the surface. Get a plan that identifies the system driving the pain — and works on it directly.

Initial Vulvodynia Pain Assessment — Edmonton

60-minute one-on-one session. Here’s what’s included:

1

Full symptom history, hormonal history, and prior treatment review

2

Pelvic floor muscle assessment and nervous system sensitization screening

3

Identification of which pain drivers are most relevant for your case

4

Clear written treatment plan with transparent pricing before you commit

No referral needed. No obligation to continue beyond the first visit.

No pressure, no contracts.

We will tell you honestly at the assessment if we don't believe you're a good candidate for this approach. If your condition needs something different, we'll refer you directly.